Southern Comfort Seafood Skillet: Cajun Salmon and Shrimp with Creamy Garlic Sauce

Southern Comfort Seafood Skillet: Cajun Salmon and Shrimp with Creamy Garlic Sauce

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Cajun Shrimp and Salmon with Garlic Cream Sauce

A restaurant-worthy skillet dish featuring spicy Cajun shrimp and salmon smothered in a rich, velvety garlic cream sauce.

5 from 1 review
Prep Time 15 mins
Cook Time 25 mins
Total Time 40 mins
Servings 4
Calories 680 kcal

📝 Ingredients

👩‍🍳 Instructions

  1. 1
    Pat salmon fillets dry with paper towels. Sprinkle 1.5 tablespoons of Cajun seasoning evenly over both sides of the salmon. In a separate bowl, toss shrimp with the remaining 1.5 tablespoons of Cajun seasoning until evenly coated. Set aside.
  2. 2
    Heat 1 tablespoon of olive oil in a large, heavy-bottomed skillet over medium-high heat until shimmering. Carefully place salmon fillets into the hot skillet. Sear for 4-5 minutes per side, depending on thickness, until golden brown and cooked through. Remove salmon and set aside on a plate, covered loosely with foil.
  3. 3
    Add the remaining 1 tablespoon of olive oil and 1 tablespoon of butter to the same skillet. Once butter is melted, add the seasoned shrimp. Cook for 2-3 minutes per side, stirring occasionally, until pink and opaque. Remove shrimp and add to the plate with the salmon.
  4. 4
    Reduce heat to medium-low. Add minced garlic to the skillet and cook for about 1 minute, stirring constantly, until fragrant. Do not burn the garlic.
  5. 5
    Pour in chicken broth, scraping up any browned bits from the pan. Simmer for 1-2 minutes. Stir in heavy cream, dried oregano, dried thyme, and optional cayenne pepper. Bring to a gentle simmer and cook for 5-7 minutes, stirring occasionally, until sauce thickens to desired consistency. Season with salt and pepper to taste.
  6. 6
    Return cooked salmon and shrimp to the skillet with the garlic cream sauce. Gently spoon sauce over the seafood and warm through for 1-2 minutes. Garnish generously with fresh chopped parsley before serving.

💡 Notes

For best results, use fresh, high-quality salmon and shrimp. Adjust Cajun seasoning and cayenne pepper to your preferred spice level. This dish is excellent served over rice, pasta, or mashed potatoes to soak up all the delicious sauce.

🥗 Nutrition (per serving)

Calories 680 kcal
Protein 52g
Total Fat 48g
Saturated Fat 24g
Carbs 10g
Fiber 2g
Sugar 2g
Sodium 850mg
Cholesterol 280mg

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